Brain Volume Changes in First-Episode Schizophrenia
نویسندگان
چکیده
منابع مشابه
Brain volume changes in first-episode schizophrenia: a 1-year follow-up study.
BACKGROUND Imaging studies of patients with schizophrenia have demonstrated that brain abnormalities are largely confined to decreases in gray matter volume and enlargement of the lateral and third ventricles. Global gray matter volume has been reported to progressively decrease in childhood-onset and chronic schizophrenia. Global gray matter volumes have not been examined longitudinally in pat...
متن کاملBrain volume changes after withdrawal of atypical antipsychotics in patients with first-episode schizophrenia.
The influence of antipsychotic medication on brain morphology in schizophrenia may confound interpretation of brain changes over time. We aimed to assess the effect of discontinuation of atypical antipsychotic medication on change in brain volume in patients. Sixteen remitted, stable patients with first-episode schizophrenia, schizoaffective or schizophreniform disorder and 20 healthy controls ...
متن کاملReduced left angular gyrus volume in first-episode schizophrenia.
OBJECTIVE Research suggests that the normal left-greater-than-right angular gyrus volume asymmetry is reversed in chronic schizophrenia. The authors examined whether angular gyrus volume and asymmetry were abnormal in patients with first-episode schizophrenia. METHOD Magnetic resonance imaging scans were obtained from 14 inpatients at their first hospitalization for psychosis and 14 normal co...
متن کاملHippocampal and superior temporal gyrus volume in first-episode schizophrenia.
T he article by Velakoulis et al 1 reported the important finding of hippocampal volume reduction in first-episode schizophrenia and interpreted it as evidence in support of a neurodevelopmental model of this disorder. The authors stated that " no [pre-vious] studies have examined the specificity of this finding to first-episode schizophrenia, compared with first-episode affective psychosis. " ...
متن کاملBrain volume in first-episode schizophrenia: systematic review and meta-analysis of magnetic resonance imaging studies.
BACKGROUND Studies of people with schizophrenia assessed using magnetic resonance imaging (MRI) usually include patients with first-episode and chronic disease, yet brain abnormalities may be limited to those with chronic schizophrenia. AIMS To determine whether patients with a first episode of schizophrenia have characteristic brain abnormalities. METHOD Systematic review and meta-analysis...
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ژورنال
عنوان ژورنال: Archives of General Psychiatry
سال: 2002
ISSN: 0003-990X
DOI: 10.1001/archpsyc.59.11.1002